This is only his 3rd draft in charge of the Packers, but so far GM Ted Thompson has either drafted players that fill an obvious need (LB A.J. Hawk) or were a good value (QB Aaron Rodgers).
The most obvious need this draft is at running back so that would be RB Marshawn Lynch. Most mock drafts expect that Lynch will be drafted by Buffalo at number 12, but NFL.com's Pat Kirwan thinks Buffalo will draft a linebacker. Buffalo lost a starting linebacker (London Fletcher-Baker) and starting cornerback (Nate Clements) in free agency, before they traded away their starting running back (Willis McGahee). They have a lot of holes to fill and could draft to fill any of those positions. Plus Buffalo really surprised everyone with their two unlikely first round picks last season.
A fellow SB Nation site Big Cat Country had a mock draft and said the Packers would select Michigan CB Leon Hall. At first it seemed wrong that they would draft a cornerback since their top three cornerbacks are strong and the only free agent signing was a cornerback too. But the Packers could use help at safety and might draft a talented cornerback and consider converting him to safety or moving CB Charles Woodson to safety. Plus at number 16, it is possible that the Packers would select the first cornerback of the draft which makes it a great position to look for a value pick.
My hunch remains that if Lynch isn't available at number 16, then Thompson looks to trade down for more picks later.