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If this were the bottom five, the Green Bay Packers attempts at tackling LaGarrette Blount would be the run away winner. But since this is the top 5 plays, let's dig a little deeper. From the play-by-play at NFL.com:
Second Quarter
(10:55) 5-J.Freeman sacked at TB 17 for -3 yards (93-E.Walden).
This 1st down play didn't slow the Buccaneers down, but Erik Walden did a great job of not falling for the fake pass attempt and zeroing in for the sack. It also helped that they didn't block him.
(5:21) 27-L.Blount up the middle to GB 13 for -3 yards (55-D.Bishop, 95-H.Green)
Near the end of the second quarter, they were driving and had a 1st down at the Packers 10 yard line. Desmond Bishop's tackle for a loss eventually forced them to settle for a field goal.
(:41) (Shotgun) 5-J.Freeman pass short left intended for 19-M.Williams INTERCEPTED by 38-T.Williams at GB 28. 38-T.Williams to GB 28 for no gain (17-A.Benn).
Another late second quarter drive was busted when Tramon Williams jumped the route for the interception. It took at least a field goal attempt away from them.
Fourth Quarter
(2:47) (Shotgun) 5-J.Freeman pass short right intended for 82-K.Winslow INTERCEPTED by 38-T.Williams at TB 41. 38-T.Williams to TB 13 for 28 yards (28-K.Lumpkin).
Tramon strikes again when the Buccaneers were trying to match scores late in the game.
(1:19) (Shotgun) 5-J.Freeman sacked at TB 33 for -5 yards (21-C.Woodson).
They had little chance of pulling off the upset by this point, but this sack by Charles Woodson effectively ended it.